Upper GI & Acid Reflux Center

Stomach & Esophagus Conditions

Advanced diagnostics and incisionless Third Space Endoscopy for Acid Reflux (GERD), Peptic Ulcers, Achalasia Cardia, and Early Gastric Polyps with Dr. Randeep Rana.

HD EndoscopyJapanese Narrow Band Imaging (NBI)
Motility Lab24-hr pH & High-Res Manometry
IncisionlessPOEM Surgery for Achalasia
Organ-PreservingESD & EMR Early Cancer Resection
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GERD & Chronic Acid Reflux

Mucosal Healing Protocols

Gastroesophageal Reflux Disease (GERD) occurs when stomach acid repeatedly escapes into the esophagus, causing burning, regurgitation, and potential esophageal injury (Barrett's esophagus).

Symptoms & Warning Signs

  • Burning sensation in the chest (heartburn) often worse after meals or lying down
  • Acidic sour liquid regurgitation into the throat or mouth
  • Chronic dry cough, throat clearing, or nighttime hoarseness
  • Difficulty or discomfort when swallowing solid food

Diagnostic Workup

  • Japanese HD Video Endoscopy with Narrow Band Imaging (NBI)
  • 24-Hour ambulatory pH-impedance monitoring for true acid exposure
  • High-Resolution Esophageal Manometry to evaluate sphincter function
  • Barium swallow study for hiatal hernia assessment

Treatment & Protocol

  • Targeted acid suppression therapy (PPIs, Potassium-competitive acid blockers)
  • Mucosal protective agents and anti-reflux lifestyle optimization
  • Endoscopic anti-reflux procedures or hiatal hernia surgical repair
  • Regular surveillance for Barrett's esophagus dysplasia prevention
Protocol curated by Dr. Randeep Rana(AIIMS & PGIMER Trained, Max Smart Hospital)
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H. Pylori Infection & Peptic Ulcers

Rapid Eradication Protocol

Helicobacter pylori is a bacterial pathogen that colonizes the stomach lining, causing chronic gastritis, painful gastric or duodenal ulcers, and increasing long-term gastric cancer risk.

Symptoms & Warning Signs

  • Gnawing, burning stomach pain between meals or during early morning hours
  • Bloating, early fullness after small meals, and frequent burping
  • Nausea, vomiting, and unexplained loss of appetite
  • Dark black tarry stools indicating upper gastrointestinal ulcer bleeding

Diagnostic Workup

  • Non-invasive Carbon-14 / Carbon-13 Urea Breath Test (UBT)
  • Stool H. Pylori Antigen test
  • Endoscopic Rapid Urease Test (RUT / CLO test) with mucosal biopsy

Treatment & Protocol

  • Evidence-based 14-day triple/quadruple antibiotic eradication regimens
  • High-dose proton pump inhibitors to promote mucosal ulcer healing
  • Confirmation of bacterial cure with post-treatment breath testing
  • Endoscopic hemoclip/cautery therapy for active ulcer hemorrhage
Protocol curated by Dr. Randeep Rana(AIIMS & PGIMER Trained, Max Smart Hospital)
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Achalasia Cardia

Incisionless POEM Surgery

Achalasia is a motility disorder where the lower esophageal sphincter fails to relax during swallowing, leading to progressive food stagnation, dilation, and severe weight loss.

Symptoms & Warning Signs

  • Progressive difficulty swallowing both solid foods and liquids (dysphagia)
  • Regurgitation of undigested food, especially when lying flat at night
  • Substernal chest pain often mistaken for cardiac angina
  • Significant unintentional weight loss and chronic coughing

Diagnostic Workup

  • High-Resolution Esophageal Manometry (Eckardt score quantification)
  • Timed Barium Swallow showing classic 'bird's beak' tapering
  • Upper GI Endoscopy to rule out pseudoachalasia or esophageal strictures

Treatment & Protocol

  • POEM (Peroral Endoscopic Myotomy) — Incisionless Third Space Endoscopy
  • Pneumatic balloon dilation for selective non-surgical candidates
  • Endoscopic Botulinum toxin injection for temporary symptom control
Protocol curated by Dr. Randeep Rana(AIIMS & PGIMER Trained, Max Smart Hospital)
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Gastric Cancer & Early Polyps

Early Resection & ESD

Early gastric neoplasms and polyps detected at a superficial stage can be curatively resected endoscopically without requiring partial or total stomach removal.

Symptoms & Warning Signs

  • Often asymptomatic in early curable stages
  • Vague indigestion, persistent dyspepsia, or post-prandial fullness
  • Unexplained iron deficiency anemia or occult blood in stool
  • Persistent upper abdominal discomfort and early satiety

Diagnostic Workup

  • High-Magnification Narrow Band Imaging (NBI) endoscopy
  • Targeted micro-biopsy for histopathology and HER2/PD-L1 profiling
  • Endoscopic Ultrasound (EUS) for precise submucosal depth assessment

Treatment & Protocol

  • Endoscopic Submucosal Dissection (ESD) for en-bloc organ-preserving resection
  • Endoscopic Mucosal Resection (EMR) for smaller benign polyps
  • Multidisciplinary oncological evaluation and staging
Protocol curated by Dr. Randeep Rana(AIIMS & PGIMER Trained, Max Smart Hospital)
Max Smart Super Speciality Hospital, Saket, New Delhi

Take the First Step Towards Digestive Wellness

Consultant Gastroenterologist, Hepatologist & advanced endoscopist at Max Smart Saket

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