Stomach & Esophagus Conditions
Advanced diagnostics and incisionless Third Space Endoscopy for Acid Reflux (GERD), Peptic Ulcers, Achalasia Cardia, and Early Gastric Polyps with Dr. Randeep Rana.
GERD & Chronic Acid Reflux
Gastroesophageal Reflux Disease (GERD) occurs when stomach acid repeatedly escapes into the esophagus, causing burning, regurgitation, and potential esophageal injury (Barrett's esophagus).
Symptoms & Warning Signs
- Burning sensation in the chest (heartburn) often worse after meals or lying down
- Acidic sour liquid regurgitation into the throat or mouth
- Chronic dry cough, throat clearing, or nighttime hoarseness
- Difficulty or discomfort when swallowing solid food
Diagnostic Workup
- Japanese HD Video Endoscopy with Narrow Band Imaging (NBI)
- 24-Hour ambulatory pH-impedance monitoring for true acid exposure
- High-Resolution Esophageal Manometry to evaluate sphincter function
- Barium swallow study for hiatal hernia assessment
Treatment & Protocol
- Targeted acid suppression therapy (PPIs, Potassium-competitive acid blockers)
- Mucosal protective agents and anti-reflux lifestyle optimization
- Endoscopic anti-reflux procedures or hiatal hernia surgical repair
- Regular surveillance for Barrett's esophagus dysplasia prevention
H. Pylori Infection & Peptic Ulcers
Helicobacter pylori is a bacterial pathogen that colonizes the stomach lining, causing chronic gastritis, painful gastric or duodenal ulcers, and increasing long-term gastric cancer risk.
Symptoms & Warning Signs
- Gnawing, burning stomach pain between meals or during early morning hours
- Bloating, early fullness after small meals, and frequent burping
- Nausea, vomiting, and unexplained loss of appetite
- Dark black tarry stools indicating upper gastrointestinal ulcer bleeding
Diagnostic Workup
- Non-invasive Carbon-14 / Carbon-13 Urea Breath Test (UBT)
- Stool H. Pylori Antigen test
- Endoscopic Rapid Urease Test (RUT / CLO test) with mucosal biopsy
Treatment & Protocol
- Evidence-based 14-day triple/quadruple antibiotic eradication regimens
- High-dose proton pump inhibitors to promote mucosal ulcer healing
- Confirmation of bacterial cure with post-treatment breath testing
- Endoscopic hemoclip/cautery therapy for active ulcer hemorrhage
Achalasia Cardia
Achalasia is a motility disorder where the lower esophageal sphincter fails to relax during swallowing, leading to progressive food stagnation, dilation, and severe weight loss.
Symptoms & Warning Signs
- Progressive difficulty swallowing both solid foods and liquids (dysphagia)
- Regurgitation of undigested food, especially when lying flat at night
- Substernal chest pain often mistaken for cardiac angina
- Significant unintentional weight loss and chronic coughing
Diagnostic Workup
- High-Resolution Esophageal Manometry (Eckardt score quantification)
- Timed Barium Swallow showing classic 'bird's beak' tapering
- Upper GI Endoscopy to rule out pseudoachalasia or esophageal strictures
Treatment & Protocol
- POEM (Peroral Endoscopic Myotomy) — Incisionless Third Space Endoscopy
- Pneumatic balloon dilation for selective non-surgical candidates
- Endoscopic Botulinum toxin injection for temporary symptom control
Gastric Cancer & Early Polyps
Early gastric neoplasms and polyps detected at a superficial stage can be curatively resected endoscopically without requiring partial or total stomach removal.
Symptoms & Warning Signs
- Often asymptomatic in early curable stages
- Vague indigestion, persistent dyspepsia, or post-prandial fullness
- Unexplained iron deficiency anemia or occult blood in stool
- Persistent upper abdominal discomfort and early satiety
Diagnostic Workup
- High-Magnification Narrow Band Imaging (NBI) endoscopy
- Targeted micro-biopsy for histopathology and HER2/PD-L1 profiling
- Endoscopic Ultrasound (EUS) for precise submucosal depth assessment
Treatment & Protocol
- Endoscopic Submucosal Dissection (ESD) for en-bloc organ-preserving resection
- Endoscopic Mucosal Resection (EMR) for smaller benign polyps
- Multidisciplinary oncological evaluation and staging
Take the First Step Towards Digestive Wellness
Consultant Gastroenterologist, Hepatologist & advanced endoscopist at Max Smart Saket